Spinal Anesthesia Thesis

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The maximum motor block level was assessed according to the modified Bromage scale.

During postoperative period, the frequency of analgesic requirement, time to the first analgesic request, and pain scores were evaluated by blind investigator.

The EA of 2-5ml/h was recontinued and effective for pain control for 3 days without no incident.

It is the first time in the medical literature that Lipid Emulsion is used for the purpose of LAR (Local Anesthesia Reversal) not connected to LAST (Local Anesthetic Systemic Toxicity).

On examination, she had diminished both touch sensory and motor power on the non-operative leg, but intact on the operative side with VAS at 2/10.

Epidural catheter was receded 2 cm and the dose was lowered and paused.

After completion of the lipid therapy, the sensory and movement of the non-operative leg regained normal after 60 min.

The severe pain recurred which needed IV morphine titration.

Previous clinical studies showed that intravenous dexmedetomidine administration prolonged the sensory and motor blocks of bupivacaine spinal analgesia.

But clinical studies about the use of intrathecal DXM with local anesthesia in humans are scarce in the literature. found that 3μg DXM added to 12 mg spinal bupivacaine produced the significant short onset of sensory and motor block as well as significantly longer duration of sensory and motor block than bupivacaine. reported that intrathecal dexmedetomidine as an adjuvant to 12.5mg bupivacaine in spinal anesthesia has a dose dependant effect on the onset and regression of sensory and motor block.


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